3.3.1.4. The pancreas

74317-004-9B143D52The pancreas produces (in addition to others) two important hormones, insulin and glucagon. They work together to maintain a steady level of glucose, or sugar, in the blood and to keep the body supplied with fuel to produce and maintain stores of energy.

Secreted hormone From cells Effect
Insulin (Primarily) β Islet cells Intake of glucose, glycogenesis and glycolysis in liver and muscle from bloodintake of lipids and synthesis of triglycerides in adipocytes Other anabolic effects
Glucagon (Also Primarily) α Islet cells glycogenolysis and gluconeogenesis in liverincreases blood glucose level
Somatostatin δ Islet cells Inhibit release of insulin
Inhibit release of glucagon Suppress the exocrine secretory action of pancreas.
Pancreatic polypeptide PP cells Self regulate the pancreas secretion activities and effect the hepatic glycogen levels.
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